AANEM News Express Related to Science News

AANEM News Express

Science News: Free-Living Physical Activity and Sedentary Behavior in Autoimmune Myasthenia Gravis: A Cross-Sectional Study

    1/7/2022
Physical activity in patients with myasthenia gravis (MG) can be limited due to fatigability and undertreated disease. However, patients with well controlled disease are recommended to participate in routine daily exercise to reduce risk of life-style related conditions. This prospective cross-sectional study looked at physical activity patterns of women with MG. 

Science News: European Academy of Neurology/Peripheral Nerve Society Guideline on Diagnosis and Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Report of a Joint Task Force-Second Revision

    12/29/2021
CIDP diagnosis is based on clinical, electrophysiological and other laboratory investigations. The EFNS/PNS diagnostic criteria (2010) for CIDP has been found to have high sensitivity and specificity. The second revision has been recently published with goal in improving diagnostic accuracy and treatment outcome.

Science News: Clinical Features and Treatment Response in Immune-Mediated Small Fiber Neuropathy with Trisulfated Heparin Disaccharide or Fibroblast Growth Factor Receptor 3 Antibodies

    12/15/2021
The objective of the article was to describe clinical features and treatment responses in cryptogenic small fiber neuropathy (SFN) cases harboring novel antibodies to trisulfated heparin disaccharide (TS-HDS) and fibroblast growth factor receptor 3 (FGFR-3).

Science News: Critical Illness Polyneuropathy, Myopathy and Neuronal Biomarkers in COVID-19 Patients: A Prospective Study

    12/15/2021
This article determines the risk factors for developing critical illness neuropathy (CIN) and/or myopathy (CIM) in 111 COVID patients admitted to an ICU in Sweden, as well as differences between COVID and non-COVID patients with ICU weakness.

Science News: Diagnostic Utility of Gold Coast Criteria in Amyotrophic Lateral Sclerosis

    12/1/2021
Existing diagnostic criteria for amyotrophic lateral sclerosis (ALS) such as El Escorial criteria (rEEC) and Awaji criteria have certain limitations, particularly for early disease or atypical presentations of ALS. A new diagnostic criterion has been proposed, with the goal of making it simpler to implement and include atypical presentations.

Science News: Charcot-Marie-Tooth Disease Misdiagnosed as a Chronic Inflammatory Demyelinating Polyradiculoneuropathy: An International Multicentric Retrospective Study

    12/1/2021
Charcot–Marie–Tooth (CMT) disease, a common hereditary polyneuropathy, has no treatment besides symptomatic relief. Authors performed a large retrospective study in 16 university hospitals in three European countries (France, Belgium, and Switzerland). Among 1,104 chronic inflammatory demyelinating polyneuropathy (CIDP) cases, there were 35 CMT patients (3.2%) misdiagnosed as CIDP.

Science News: Assessing Diagnostic and Severity Grading Accuracy of Ultrasound Measurements for Carpal Tunnel Syndrome Compared to Electrodiagnostics

    11/16/2021
Prospective study of 95, 18-80 y.o. patients referred for EDX of idiopathic CTS. Exclusion criteria for prior CTS and other concomitant confounding factors.  CSI performed and Bland criteria used to assess for severity.

Science News: Effect of High-Frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial

    11/16/2021
Nevro's SENZA-PDN study, RCT of spinal cord stimulation treatment conducted for PDN-painful diabetic polyneuropathy, compares 10 kHz SCS plus Conventional Medical Management (CMM) to CMM alone in 216 patients at 18 centers in the United States.

Science News: Skeletal Muscle and Peripheral Nerve Histopathology in COVID-19

    11/4/2021
This study discusses spectrum of skeletal muscle and nerve pathology of patients who died following SARS-CoV-2 infection.
Psoas muscle and femoral nerve sampled from 35 consecutive autopsies of patients who died following SARS-CoV-2 infection were collected and analyzed.
 

Science News: Impact of Coronavirus Disease 2019 in a French Cohort of Myasthenia Gravis

    11/4/2021
Among 3,558 patients with MG registered in the French database for rare disorders, 34 (0.96%) had COVID-19. The mean age at COVID-19 onset was 55.0 ± 19.9 years (mean MG duration: 8.5 ± 8.5 years). By the end of the study period, 28 patients recovered from COVID-19, 1 remained affected, and 5 died.


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